Intestinal lipid absorption

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Intestinal lipid absorption.

Our knowledge of the uptake and transport of dietary fat and fat-soluble vitamins has advanced considerably. Researchers have identified several new mechanisms by which lipids are taken up by enterocytes and packaged as chylomicrons for export into the lymphatic system or clarified the actions of mechanisms previously known to participate in these processes. Fatty acids are taken up by enterocy...

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Intestinal lipid absorption and transport.

The purpose of this review is to update the reader on our current knowledge of the digestion, uptake, and transport of dietary lipid. In particular, it discusses how intestinal lipid transporters may play a role in the uptake of lipids by the enterocytes, and how chylomicrons are formed in the enterocytes and packaged for export into the lymphatic system through exocytosis. The classification a...

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Lipid absorption and intestinal lipoprotein formation.

Lipid absorption is a complex process which involves coordinated gastric, intestinal, biliary and pancreatic function. Emulsification of dietary lipid occurs in the stomach and upper intestine where a series of enzymic events also occur. Phospholipids are digested by phospholipases. Colipase anchors lipase to the emulsion surface overcoming the interfering effect of bile salts. The products of ...

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Intestinal Lipid Absorption in the Nephrotic Rat1’2

There is limited data on intestinal lipid absorption in the nephrotic syndrome. This study investigated whether the efficiency of intestinal lipid absorption is altered in nephrotic lymph-fistula rats. The nephrotic syndrome was induced in nine Sprague-Dawley rats by an iv injection of puromycin aminonucleoside in saline; seven control rats received saline only. At 10 to 14 days after injection...

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Development and physiological regulation of intestinal lipid absorption. III. Intestinal transporters and cholesterol absorption.

Intestinal cholesterol absorption is modulated by transport proteins in enterocytes. Cholesterol uptake from intestinal lumen requires several proteins on apical brush-border membranes, including Niemann-Pick C1-like 1 (NPC1L1), scavenger receptor B-I, and CD36, whereas two ATP-binding cassette half transporters, ABCG5 and ABCG8, on apical membranes work together for cholesterol efflux back to ...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism

سال: 2009

ISSN: 0193-1849,1522-1555

DOI: 10.1152/ajpendo.90899.2008